Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419304 | 0.87 | MAOA (0.51) | KDM4EMAPTLMNAJAK2JAK3 | |
| SCHEMBL27980556 | 0.85 | MAPK14 (0.51) | MAPK14MAPTPOLBKMT2AGAA | |
| SCHEMBL12287690 | 0.84 | MAOA (0.52) | KDM4EMAPTSMN1; SMN2JAK2JAK3 | |
| SCHEMBL10289638 | 0.83 | JAK2 (0.48) | KDM4EJAK2JAK3KMT2AMAOA | |
| SCHEMBL5538390 | 0.83 | KDM4E (0.48) | KDM4EMAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL14465575 | 0.82 | ALOX15 (0.50) | KDM4EJAK2JAK3KMT2AMAOA | |
| SCHEMBL16858478 | 0.82 | GPR84 (0.49) | KDM4EJAK2JAK3KMT2AMAOA | |
| SCHEMBL397748 | 0.82 | JAK2 (0.50) | KDM4EJAK2JAK3KMT2AMAOA | |
| SCHEMBL6419306 | 0.82 | KDM4E (0.49) | KDM4ESMN1; SMN2JAK2JAK3KMT2A | |
| SCHEMBL4500812 | 0.81 | ALDH1A1 (0.58) | KDM4EMAPK14MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081335-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |