Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 7/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446676 | 0.91 | LMNA (0.53) | HTR7LMNAPOLBBCL2BAK1 | |
| SCHEMBL1958329 | 0.82 | HTR7 (0.55) | HTR7LMNAPOLBBCL2BAK1 | |
| SCHEMBL3954643 | 0.80 | CACNA1G (0.55) | HTR7LMNAPOLBBCL2BAK1 | |
| SCHEMBL6500422 | 0.79 | CACNA2D1 (0.56) | HTR7LMNAPOLBBCL2BAK1 | |
| SCHEMBL1137904 | 0.78 | HTR7 (0.52) | HTR7LMNAPOLBBCL2BAK1 | |
| Hydrochloric Acid SCHEMBL5624913 | 0.77 | HTR7 (0.51) | HTR7LMNAPOLBBCL2BAK1 | |
| SCHEMBL376877 | 0.77 | VEGFA (0.58) | HTR7POLBBCL2BAK1TACR2 | |
| SCHEMBL219876 | 0.77 | HRH1 (0.59) | HTR7BCL2BAK1ALDH1A1BCL2L1 | |
| Hydrochloric Acid SCHEMBL5686168 | 0.76 | HRH1 (0.60) | HTR7BCL2BAK1ALDH1A1BCL2L1 | |
| SCHEMBL1569359 | 0.76 | HTR7 (0.50) | HTR7BCL2BAK1ALDH1A1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297122-A1 | NEW PROCESS FOR THE PREPARATION OF LEVOCETIRIZINE AND INTERMEDIATES THEREOF | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009150147-A1 | NEW PROCESS FOR THE PREPARATION OF LEVOCETIRIZINE AND INTERMEDIATES THEREOF | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2009-12-17 | — | — | WO | disclosed |