Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 4/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958329 | 0.82 | HTR7 (0.55) | SIGMAR1ALDH1A1BCL2BAK1HTR7 | |
| SCHEMBL1446676 | 0.80 | LMNA (0.53) | ALDH1A1MAPTTSHRMAPK1BCL2 | |
| SCHEMBL1446715 | 0.80 | HTR7 (0.51) | ALDH1A1MAPTTSHRMAPK1BCL2 | |
| SCHEMBL6500422 | 0.79 | CACNA2D1 (0.56) | ALDH1A1MAPTTSHRMAPK1BCL2 | |
| SCHEMBL10929641 | 0.78 | HTR7 (0.54) | ALDH1A1BCL2BAK1HTR7BCL2L1 | |
| SCHEMBL9178963 | 0.78 | CACNA1G (0.53) | CACNA1GBCL2BAK1HTR7BCL2L1 | |
| SCHEMBL15224158 | 0.78 | SIGMAR1 (0.73) | CACNA1GSIGMAR1ALDH1A1HTR7LMNA | |
| SCHEMBL2116073 | 0.77 | HTR7 (0.53) | CACNA1GALDH1A1BCL2BAK1HTR7 | |
| SCHEMBL3959128 | 0.77 | CACNA1G (0.64) | CACNA1GSIGMAR1ALDH1A1MAPTTSHR | |
| SCHEMBL1138135 | 0.76 | HTR7 (0.60) | SIGMAR1ALDH1A1MAPTBCL2BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035307-A2 | NOVEL COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME FOR INHIBITING PAIN | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2009-03-19 | — | — | WO | claimed |
| WO-2009035307-A2 | NOVEL COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME FOR INHIBITING PAIN | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2009-03-19 | — | — | WO | disclosed |