SCHEMBL14477997

SCHEMBL14477997

COC(=O)C(C(C)=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
ATM Q13315 1/20 0.44
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
BCAT1 P54687 1/20 0.42
HTT P42858 1/20 0.41
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MMP1 P03956 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9394876 0.83 ATM (0.52) KMT2AATMLMNATSHRHSD17B10
SCHEMBL16186175 0.83 KMT2A (0.43) KMT2AATMLMNATSHRHSD17B10
SCHEMBL17472101 0.82 ATM (0.48) KMT2AATMLMNATSHRHSD17B10
SCHEMBL18269676 0.82 ATM (0.45) KMT2AATMLMNATSHRHSD17B10
SCHEMBL25725872 0.82 KMT2A (0.42) KMT2AATMLMNATSHRHSD17B10
SCHEMBL6097619 0.79 CA12 (0.51) KMT2AATMLMNATSHRHSD17B10
SCHEMBL5281607 0.77 KMT2A (0.47) KMT2AATMLMNATSHRHSD17B10
SCHEMBL16884985 0.76 CA12 (0.51) KMT2AATMLMNATSHRHSD17B10
SCHEMBL5312084 0.75 LMNA (0.42) KMT2AATMLMNATSHRHSD17B10
SCHEMBL26047552 0.75 ATM (0.50) KMT2AATMLMNATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241025-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS CRESCENTA BIOSCIENCES (US) 2023-08-03 US disclosed
WO-2023126297-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2023-07-06 WO disclosed
WO-2022010951-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS CRESCENTA BIOSCIENCES (US) 2022-01-13 WO disclosed
WO-2022008419-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2022-01-13 WO disclosed
WO-2022010948-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF VIRAL DISEASES CRESCENTA BIOSCIENCES (US) 2022-01-13 WO disclosed
WO-2021263246-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF CRESCENTA BIOSCIENCES (US) 2021-12-30 WO disclosed
EP-3253745-B1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS PIRAMAL ENTPR LTD (IN) 2021-09-29 EP disclosed
WO-2021150645-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF CRESCENTA BIOSCIENCES (US) 2021-07-29 WO disclosed
EP-3191463-B1 FUSED HETEROCYCLIC COMPOUNDS AS GPR120 AGONISTS PIRAMAL ENTPR LTD (IN) 2019-10-30 EP disclosed
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-01 US disclosed
WO-2013001297-A1 BINDING INHIBITORS OF THE BETA.TRANSDUCIN REPEAT - CONTAINING PROTEIN ITI SCOTLAND LIMITED (GB) 2013-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241025-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS FABP1, FABP4, FABP5 KMT2A 4004/4885ATM 4881/4885LMNA 2753/4885
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS GPR119, GPR55, GPR180 KMT2A 4028/4885ATM 3652/4885LMNA 3487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.