Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825100 | 0.78 | — | — | |
| SCHEMBL14764484 | 0.74 | CA2 (0.40) | ALDH1A1 | |
| SCHEMBL11331363 | 0.72 | MAPT (0.45) | — | |
| SCHEMBL891222 | 0.72 | — | — | |
| SCHEMBL4379448 | 0.71 | — | — | |
| SCHEMBL28420028 | 0.71 | TDP1 (0.41) | TDP1ALDH1A1 | |
| SCHEMBL8458707 | 0.71 | MAPT (0.48) | — | |
| SCHEMBL11329644 | 0.71 | MAPT (0.48) | — | |
| SCHEMBL5158482 | 0.71 | MAPT (0.48) | — | |
| SCHEMBL4343852 | 0.70 | TDP1 (0.39) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016011920-A1 | ALYSINE MONOMETHYLATED DERIVATIVE AND CORRESPONDING ANTIBODY AND USE THEREOF | PMT BIOLABS INC (CN) | 2016-01-28 | — | — | WO | disclosed |
| WO-2011035355-A1 | NOVEL ANTIMALARIAL 3-AZABICYCLO[3.2.2]NONANE DERIVATIVES | UNIVERSITY OF GRAZ (AT) | 2011-03-31 | — | — | WO | disclosed |
| EP-2301627-A1 | Novel antimalarial 3-azabicyclo[3.2.2]nonane derivatives | University of Graz (AT) | 2011-03-30 | — | — | EP | disclosed |
| US-7091313-B2 | Synthesis of template-fixed β-hairpin loop mimetics | UNIVERSITAT ZURICH (CH) | 2006-08-15 | — | — | US | disclosed |
| US-7030135-B2 | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2006-04-18 | — | — | US | disclosed |
| US-20050181454-A1 | Synthesis of template-fixed beta-hairpin loop mimetics | UNIVERSITY OF ZURICH AND POLYPHOR AG | 2005-08-18 | — | — | US | disclosed |
| US-20030199501-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2003-10-23 | — | — | US | disclosed |
| US-4235913-A | ANALGESICS, TRANQUILIZERS | PFIZER INC. (US) | 1980-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199501-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD3B1, HSD17B1 | TDP1 684/4885ALDH1A1 409/4885 |
| US-20050181454-A1 | Synthesis of template-fixed beta-hairpin loop mimetics | EBPL, QPCTL, SUCLG2 | TDP1 3470/4885ALDH1A1 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.