Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9520975 | 0.76 | MTNR1A (0.47) | MTNR1AMTNR1BRECQLCES1MEN1 | |
| Malonic Acid SCHEMBL1576831 | 0.76 | AKT1 (0.45) | MTNR1AMTNR1BCES1MEN1KMT2A | |
| SCHEMBL10397770 | 0.75 | AKR1C3 (0.50) | MTNR1AMTNR1BCES1MEN1KMT2A | |
| SCHEMBL10397769 | 0.75 | AKR1C3 (0.50) | MTNR1AMTNR1BCES1MEN1KMT2A | |
| SCHEMBL88322 | 0.74 | ALDH1A1 (0.46) | MTNR1AMTNR1BRECQLCES1MEN1 | |
| SCHEMBL44266 | 0.73 | MTNR1A (0.42) | MTNR1AMTNR1BCES1MAPK1TDP1 | |
| SCHEMBL14488786 | 0.73 | CES1 (0.53) | MTNR1AMTNR1BCES1MEN1KMT2A | |
| SCHEMBL183824 | 0.71 | KDM1A (0.42) | MTNR1AMTNR1BCES1SMN1; SMN2TDP1 | |
| SCHEMBL2910666 | 0.71 | RECQL (0.67) | MTNR1AMTNR1BRECQLMEN1KMT2A | |
| SCHEMBL2910667 | 0.71 | RECQL (0.67) | MTNR1AMTNR1BRECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299379-B1 | PENTADIENAMIDE PAF-ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |