Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1452441 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP2C9ALOX12KMT2AMYC | |
| SCHEMBL18715445 | 0.85 | ALDH1A1 (0.39) | KDM4CMEN1KMT2AFFAR1SMN1; SMN2 | |
| SCHEMBL27932099 | 0.79 | THRB (0.38) | KMT2AFFAR1SMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL4061116 | 0.79 | CA12 (0.32) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL978600 | 0.79 | KDM4C (0.50) | KDM4CCYP3A4CYP2C9ALOX12MEN1 | |
| SCHEMBL9223049 | 0.75 | CYP3A4 (0.60) | KDM4CCYP3A4CYP2C9ALOX12MYC | |
| SCHEMBL10702548 | 0.74 | ALDH1A1 (0.54) | KMT2ASMN1; SMN2ALDH1A1ALOX15CA12 | |
| SCHEMBL27931995 | 0.72 | TP53 (0.35) | CYP2C9MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2556230 | 0.72 | HPGD (0.46) | CYP3A4CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5951434 | 0.72 | BCAT2 (0.53) | KDM4CMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910744-B2 | Pyrazole and Pyrimidine groups are introduced on aromatic phosphine; (3-bromophenyl)methyl ketone and ethylene glycol cyclize to [3-(2-methyl-1,3-dioxolane-2-yl)phenyl]diphenylphosphane; adding hydrazine monohydrate, then oxidizing with hydrogen peroxide; [3-(3-Pyrazolyl)phenyl]diphenylphosphane oxide | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENT II KG (DE) | 2011-03-22 | — | — | US | disclosed |
| EP-1805193-B1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED PHOSPHANES | ZYLUM BETEILIGUNGSGMBH & CO PATENTE II KG (DE) | 2010-12-29 | — | — | EP | disclosed |
| US-20080221335-A1 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1805193-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED PHOSPHANES, AND SUBSTITUTED PHOSPHANES PRODUCED ACCORDING TO SAID METHOD | Technische Universität Chemnitz (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006045272-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED PHOSPHANES, AND SUBSTITUTED PHOSPHANES PRODUCED ACCORDING TO SAID METHOD | TECHNISCHE UNIVERSITÄT CHEMNITZ (DE) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221335-A1 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method | SCLY, SELENOI, TST | KDM4C 1758/4885CYP3A4 1370/4885CYP2C9 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.