SCHEMBL999563

SCHEMBL999563

Nc1ccc(CS(=O)(=O)F)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.60
PRSS1 P07477 1/20 0.60
PRSS2 P07478 1/20 0.60
ELANE P08246 1/20 0.60
PRTN3 P24158 1/20 0.60
PRSS3 P35030 1/20 0.60
RECQL P46063 1/20 0.47
TSHR P16473 5/20 0.46
CYP3A4 P08684 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GFER P55789 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.44
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA9 Q16790 4/20 0.42
CA12 O43570 3/20 0.42
CA14 Q9ULX7 2/20 0.42
LMNA P02545 1/20 0.42
MPO P05164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1056876 0.98 FAAH (0.58) FAAHPRSS1PRSS2ELANEPRTN3
SCHEMBL3900282 0.82 F2 (0.64) FAAHPRSS1PRSS2ELANEPRTN3
SCHEMBL1449580 0.80 TSHR (0.50) RECQLTSHRCYP3A4TDP1ALDH1A1
SCHEMBL10760737 0.80 ALDH1A1 (0.50) FAAHPRSS1PRSS2ELANEPRTN3
SCHEMBL2984207 0.78 CA1 (0.62) RECQLTSHRCYP3A4TDP1ALDH1A1
SCHEMBL514597 0.78 RECQL (0.48) RECQLTSHRCYP3A4TDP1ALDH1A1
SCHEMBL9421733 0.78 FAAH (0.62) FAAHPRSS1PRSS2ELANEPRTN3
SCHEMBL1335821 0.76 TSHR (0.50) RECQLTSHRCYP3A4TDP1ALDH1A1
SCHEMBL514596 0.76 RECQL (0.47) RECQLTSHRCYP3A4TDP1ALDH1A1
SCHEMBL9421731 0.76 FAAH (0.60) FAAHPRSS1PRSS2ELANEPRTN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114605519-B Method for extracting H factor 四川远大蜀阳药业有限责任公司 2023-10-31 CN claimed
CN-114605519-A Method for extracting H factor 四川远大蜀阳药业有限责任公司 2022-06-10 CN claimed
US-8333985-B2 Non-glycerol stabilized bone graft WARSAW ORTHOPEDIC, INC. (US) 2012-12-18 US claimed
US-20070178158-A1 Stabilized bone graft WARSAW ORTHOPEDIC, INC. 2007-08-02 US claimed
JP-2007519496-A 2007-07-19 JP claimed
EP-1708651-A1 STABILIZED BONE GRAFT Osteotech, Inc., (US) 2006-10-11 EP claimed
WO-2005072656-A1 STABILIZED BONE GRAFT OSTEOTECH, INC. (US) 2005-08-11 WO claimed
EP-0878551-B1 Enhancement of the factor-VII sensitivity of a thromboplastin reagent DADE BEHRING MARBURG GMBH (DE) 2005-01-12 EP claimed
EP-1434608-A2 IMPROVED BONE GRAFT Osteotech, Inc. (US) 2004-07-07 EP claimed
US-20030143258-A1 Bone graft WARSAW ORTHOPEDIC, INC. 2003-07-31 US claimed
WO-2003030956-A2 IMPROVED BONE GRAFT OSTEOTECH, INC. (US) 2003-04-17 WO claimed
US-6376209-B2 HEAT TREATMENT DADE BEHRING MARBURG GMBH (DE) 2002-04-23 US claimed
US-20020012958-A1 INCREASING THE FVII SENSITIVITY OF A THROMBOPLASTIN REAGENT DADE BEHRING MARBURG GMBH (DE) 2002-01-31 US claimed
EP-0878551-A2 Enhancement of the factor-VII sensitivity of a thromboplastin reagent Dade Behring Marburg GmbH (DE) 1998-11-18 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
JP-8245404-A None JP disclosed
CN-114605519-B Method for extracting H factor 四川远大蜀阳药业有限责任公司 2023-10-31 CN disclosed
US-5120537-A FACTOR XA BASED ANTICOAGULANT COMPOSITIONS OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 1992-06-09 US disclosed
EP-0477274-A1 FACTOR Xa BASED ANTICOAGULANT COMPOSITIONS. OKLAHOMA MED RES FOUND (US) 1992-04-01 EP disclosed
WO-1990015619-A1 FACTOR Xa BASED ANTICOAGULANT COMPOSITIONS OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 1990-12-27 WO disclosed