Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 12/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387481 | 0.89 | F10 (0.40) | GBA1CA12CA1CA2CA9 | |
| SCHEMBL14503227 | 0.85 | PTGS2 (0.56) | GBA1CA12CA1CA2CA9 | |
| SCHEMBL14503143 | 0.85 | PTGS2 (0.56) | GBA1CA12CA1CA2CA9 | |
| SCHEMBL14503584 | 0.83 | ALDH1A1 (0.51) | GBA1CA12CA1CA2CA9 | |
| SCHEMBL14503562 | 0.83 | GBA1 (0.48) | GBA1CA12CA1CA2CA9 | |
| SCHEMBL5391472 | 0.82 | RAB9A (0.43) | GBA1KDM4EALDH1A1LMNAF10 | |
| SCHEMBL14503630 | 0.81 | KMT2A (0.45) | GBA1KDM4EALDH1A1F10CTNNB1 | |
| SCHEMBL14503574 | 0.79 | PTGS2 (0.48) | GBA1CA12CA1CA2CA9 | |
| SCHEMBL14503585 | 0.79 | CA12 (0.46) | GBA1CA12CA1CA2CA9 | |
| SCHEMBL14503582 | 0.78 | PTGS2 (0.51) | GBA1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |