Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391472 | 0.84 | RAB9A (0.43) | KMT2ARAB9ACTNNB1TCF7L2MAPT | |
| SCHEMBL14503581 | 0.81 | GBA1 (0.49) | CTNNB1TCF7L2MAPTGBA1POLB | |
| SCHEMBL14503139 | 0.79 | PTGS2 (0.47) | KMT2ARAB9ACTNNB1TCF7L2MAPT | |
| SCHEMBL5387481 | 0.77 | F10 (0.40) | KMT2ARAB9AMAPTGBA1MEN1 | |
| SCHEMBL14503626 | 0.73 | CTNNB1 (0.41) | KMT2ARAB9ACTNNB1TCF7L2MAPT | |
| SCHEMBL14503615 | 0.71 | GBA1 (0.48) | KMT2AMAPTGBA1MEN1NPSR1 | |
| SCHEMBL14503191 | 0.70 | PTGS2 (0.57) | KMT2ARAB9ACTNNB1TCF7L2MAPT | |
| SCHEMBL14503163 | 0.70 | PTGS2 (0.57) | KMT2ARAB9ACTNNB1TCF7L2MAPT | |
| SCHEMBL14503583 | 0.70 | MAPT (0.45) | KMT2ARAB9AMAPTGBA1POLB | |
| SCHEMBL14503676 | 0.70 | PTGS2 (0.52) | KMT2ARAB9ACTNNB1TCF7L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |