Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503562 | 0.93 | GBA1 (0.48) | GBA1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5391086 | 0.89 | NAMPT (0.40) | GBA1LMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL14503163 | 0.83 | PTGS2 (0.57) | GBA1MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL14503191 | 0.83 | PTGS2 (0.57) | GBA1MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL5445977 | 0.81 | SMN1; SMN2 (0.42) | GBA1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14503628 | 0.80 | MAPT (0.49) | GBA1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14503676 | 0.79 | PTGS2 (0.52) | GBA1MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL14503550 | 0.78 | ACHE (0.43) | GBA1MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL14503398 | 0.78 | LMNA (0.58) | GBA1MAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL14503548 | 0.78 | PTGS2 (0.53) | GBA1MAPTLMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |