Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506374 | 0.81 | ATM (0.43) | ATMELANEERN1RAB9AMEN1 | |
| SCHEMBL13451644 | 0.78 | PDE10A (0.41) | ERN1MEN1KMT2AMAPTTSHR | |
| SCHEMBL8879814 | 0.75 | GCGR (0.41) | ELANERAB9AGAAKMT2AMAPT | |
| SCHEMBL8877348 | 0.75 | PDE10A (0.50) | MEN1KMT2ATSHRDHODHPDE10A | |
| SCHEMBL23682827 | 0.75 | ERN1 (0.54) | ERN1MEN1GAAKMT2AMAPT | |
| SCHEMBL1102408 | 0.74 | KDM4E (0.50) | ATMRAB9AGAAKMT2AMAPT | |
| SCHEMBL14625667 | 0.74 | KDM4E (0.46) | ATMELANEERN1RAB9AMEN1 | |
| SCHEMBL14533531 | 0.74 | GCGR (0.43) | ELANEMEN1GAAKMT2AMAPT | |
| SCHEMBL8878762 | 0.73 | ERN1 (0.53) | ELANEERN1RAB9AMEN1NPC1 | |
| SCHEMBL7127697 | 0.71 | GPR3 (0.50) | ERN1MEN1GAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105884-A1 | Opiate analogs selective for the delta-opioid receptor | WELSH WILLIAM J | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105884-A1 | Opiate analogs selective for the delta-opioid receptor | OPRM1, OPRD1, OPRK1 | ATM 4464/4885ELANE 1833/4885ERN1 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.