Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507088 | 0.81 | ALDH1A1 (0.41) | IKBKBMEN1KMT2AAKT1PIK3CA | |
| SCHEMBL14507082 | 0.80 | NR1I2 (0.51) | MEN1KMT2ANR1I2C1RCA12 | |
| SCHEMBL14507077 | 0.79 | HSP90AA1 (0.41) | IKBKBMEN1KMT2AAURKAHSP90AA1 | |
| SCHEMBL28886710 | 0.77 | AURKA (0.55) | MEN1KMT2AAURKAHSP90AA1PRKACA | |
| SCHEMBL5471322 | 0.75 | L3MBTL1 (0.46) | MEN1KMT2AAKT1PIK3CAMTOR | |
| SCHEMBL24309874 | 0.74 | MAPK1 (0.52) | MEN1KMT2ANR1I2HPGDL3MBTL1 | |
| SCHEMBL10973666 | 0.72 | GSK3B (0.55) | MEN1KMT2AAURKAHSP90AA1PRKACA | |
| SCHEMBL5462677 | 0.72 | AKT1 (0.39) | MEN1KMT2AAKT1PIK3CAMTOR | |
| SCHEMBL30299691 | 0.72 | AURKA (0.46) | MEN1KMT2AAURKAHSP90AA1PRKACA | |
| SCHEMBL14507073 | 0.70 | GRM1 (0.52) | MEN1KMT2AAURKAHSP90AA1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | IKBKB 996/4885MEN1 2400/4885KMT2A 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.