Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507076 | 0.79 | IKBKB (0.46) | HSP90AA1AURKAPRKACAADORA2AHPGD | |
| SCHEMBL30299522 | 0.76 | MAPT (0.50) | HSP90AA1AURKAPRKACAADORA2AMEN1 | |
| SCHEMBL28886710 | 0.74 | AURKA (0.55) | HSP90AA1AURKAPRKACAADORA2AMEN1 | |
| SCHEMBL14507088 | 0.73 | ALDH1A1 (0.41) | HSP90AA1AURKAPRKACAADORA2AHPGD | |
| SCHEMBL3822620 | 0.71 | HSP90AA1 (0.61) | HSP90AA1HPGDUSP2HSD17B10KMT2A | |
| SCHEMBL10973666 | 0.70 | GSK3B (0.55) | HSP90AA1AURKAPRKACAADORA2AHPGD | |
| SCHEMBL30299691 | 0.70 | AURKA (0.46) | HSP90AA1AURKAPRKACAADORA2AMEN1 | |
| SCHEMBL28144690 | 0.70 | HSP90AA1 (0.50) | HSP90AA1AURKAPRKACAADORA2AMEN1 | |
| SCHEMBL14882786 | 0.69 | KDM4E (0.56) | HSP90AA1HPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL3174757 | 0.69 | HSP90AA1 (0.57) | HSP90AA1HPGDUSP2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | HSP90AA1 2188/4885AURKA 4310/4885PRKACA 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.