Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 3/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | NOS1 | P29475 | 6/20 | 0.46 |
| ▸ | NOS3 | P29474 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ARG2 | P78540 | 4/20 | 0.43 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533751 | 0.95 | DDAH1 (0.53) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL30508517 | 0.89 | NOS3 (0.57) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL6625304 | 0.88 | DDAH1 (0.60) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL25660351 | 0.88 | DDAH1 (0.60) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL25660613 | 0.85 | NOS3 (0.54) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL21335891 | 0.83 | GSR (0.48) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL21261917 | 0.82 | DDAH1 (0.46) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL21261918 | 0.82 | DDAH1 (0.46) | DDAH1GSRNOS2NOS1NOS3 | |
| Lysine SCHEMBL28931663 | 0.82 | GSR (0.59) | DDAH1GSRNOS2NOS1NOS3 | |
| SCHEMBL25660441 | 0.82 | DDAH1 (0.58) | DDAH1GSRNOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20070105755-A1 | One pot desialylation and glycopegylation of therapeutic peptides | NEOSE TECHNOLOGIES, INC. (US) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105755-A1 | One pot desialylation and glycopegylation of therapeutic peptides | UGGT1, PTMS, GALNT1 | DDAH1 1439/4885GSR 2639/4885NOS2 2876/4885 |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | DDAH1 1985/4885GSR 1986/4885NOS2 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.