Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705118 | 0.89 | GAA (0.65) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL863133 | 0.89 | TAS2R38 (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL14872243 | 0.89 | TAS2R38 (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL26156233 | 0.87 | MAPT (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL21985779 | 0.87 | TAS2R38 (0.60) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL10189868 | 0.87 | EPHX1 (0.60) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL28294619 | 0.87 | TAS2R38 (0.60) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11718858 | 0.87 | SMN1; SMN2 (0.67) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11738124 | 0.87 | MEN1 (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL14872162 | 0.87 | TAS2R38 (0.60) | TAS2R38ALDH1A1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070098643-A1 | Oligomers of gadolinium chelates, their applicationascontrast products in magnetic resonance imaging and their synthesis intermediates | GUERBET (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098643-A1 | Oligomers of gadolinium chelates, their applicationascontrast products in magnetic resonance imaging and their synthesis intermediates | MGAT2, MGAT1, MGAT3 | TAS2R38 3832/4885ALDH1A1 3281/4885MAPT 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.