Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511451 | 0.89 | TAS2R38 (0.75) | TAS2R38TDP1CYP3A4CYP2C19MEN1 | |
| SCHEMBL1278440 | 0.83 | ALDH1A1 (0.61) | TAS2R38TDP1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11410456 | 0.82 | CYP1A2 (0.59) | TDP1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL1276739 | 0.82 | KMT2A (0.79) | TAS2R38TDP1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10882395 | 0.81 | ALDH1A1 (0.59) | TAS2R38TDP1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7213273 | 0.80 | NPC1 (0.61) | TDP1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL8705118 | 0.80 | GAA (0.65) | TAS2R38CYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL14872243 | 0.80 | TAS2R38 (0.62) | TAS2R38CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL1454275 | 0.79 | TDP1 (0.65) | TDP1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL11718858 | 0.78 | SMN1; SMN2 (0.67) | TAS2R38TDP1CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295236-A1 | COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS | PHARMA MAR, S.A. (ES) | 2023-09-21 | — | — | US | disclosed |
| US-20230295236-A1 | COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS | PHARMA MAR, S.A. (ES) | 2023-09-21 | — | — | US | disclosed |
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
| CN-112574054-B | Efficient nitriding reagent and application thereof | 北京大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| WO-2022086079-A1 | DERIVATIVE OF SEMICARBAZONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | 고려대학교 산학협력단 | 2022-04-28 | — | — | WO | disclosed |
| CN-108570038-B | Dihydroquinoxaline bromodomain recognition protein inhibitor, preparation method and application thereof | 中国科学院上海药物研究所 | 2021-09-28 | — | — | CN | disclosed |
| WO-2021175857-A1 | COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS | PHARMA MAR, S.A. (ES) | 2021-09-10 | — | — | WO | disclosed |
| WO-2021175829-A1 | COMPOUNDS FOR USE IN AUTOIMMUNE CONDITIONS | PHARMA MAR, S.A. (ES) | 2021-09-10 | — | — | WO | disclosed |
| WO-2021175826-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CORONAVIRUS INFECTION | PHARMA MAR, S.A. (ES) | 2021-09-10 | — | — | WO | disclosed |
| EP-2258366-A2 | Quinoline derivatives and quinazoline derivatives capable of inhibiting autophosphorylation of hepatocyte growth factor receptors, and pharmaceutical composition comprising the same | Kirin Pharma Kabushiki Kaisha (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-20100179132-A1 | CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS | PTC THERAPEUTICS, INC. | 2010-07-15 | — | — | US | disclosed |
| US-20100179132-A1 | CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS | PTC THERAPEUTICS, INC. | 2010-07-15 | — | — | US | disclosed |
| US-20100158858-A1 | ADMINISTRATION OF CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISEASES | PTC THERAPEUTICS, INC. | 2010-06-24 | — | — | US | disclosed |
| US-7601840-B2 | Carboline derivatives useful in the inhibition of angiogenesis | PTC THERAPEUTICS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20090023720-A1 | 2-Amino 1H-Imidazo Ring Systems and Methods | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-22 | — | — | US | disclosed |
| US-20090023720-A1 | 2-Amino 1H-Imidazo Ring Systems and Methods | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-22 | — | — | US | disclosed |
| US-20070281962-A2 | Administering 1,2,3,6-tetrasubstituted pyrido[3,4-b]indoles to inhibit the 5'-untranslated region-dependent translation; anticarcinogenic agents; retinopathy, rheumatoid arthritis, psoriasis, atherosclerosis, obesity, macular degeneration | PCT THERAPEUTICS, INC. (US) | 2007-12-06 | — | — | US | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-4540786-A | Preparation of 2-chloro-3-cyano-quinolines | THE DOW CHEMICAL COMPANY (US) | 1985-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158858-A1 | ADMINISTRATION OF CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISEASES | RNMT, VEGFA, VHL | TAS2R38 4056/4885TDP1 2369/4885CYP1A2 2360/4885 |
| US-20230295236-A1 | COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS | TLR4, TLR3, TLR2 | TAS2R38 1962/4885TDP1 3579/4885CYP1A2 1380/4885 |
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | VIP, NGLY1, GRPR | TAS2R38 1165/4885TDP1 4302/4885CYP1A2 4854/4885 |
| US-20090023720-A1 | 2-Amino 1H-Imidazo Ring Systems and Methods | IL2, IL2RA, IL4I1 | TAS2R38 2942/4885TDP1 3141/4885CYP1A2 1349/4885 |
| US-20070281962-A2 | Administering 1,2,3,6-tetrasubstituted pyrido[3,4-b]indoles to inhibit the 5'-untranslated region-dependent translation; anticarcinogenic agents; retinopathy, rheumatoid arthritis, psoriasis, atherosclerosis, obesity, macular degeneration | VEGFA, FLT4, MIF | TAS2R38 2004/4885TDP1 1284/4885CYP1A2 3938/4885 |
| US-20100179132-A1 | CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS | VEGFA, FLT4, PGF | TAS2R38 4544/4885TDP1 3761/4885CYP1A2 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.