Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511451 | 0.87 | TAS2R38 (0.75) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL28294619 | 0.81 | TAS2R38 (0.60) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL863133 | 0.78 | TAS2R38 (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL14872243 | 0.78 | TAS2R38 (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL8705118 | 0.78 | GAA (0.65) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL14872162 | 0.76 | TAS2R38 (0.60) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11738124 | 0.76 | MEN1 (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11718858 | 0.76 | SMN1; SMN2 (0.67) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL10189868 | 0.76 | EPHX1 (0.60) | TAS2R38ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL26156233 | 0.76 | MAPT (0.62) | TAS2R38ALDH1A1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3650470-A1 | NOVEL ANTI-HUMAN CEACAM5 ANTIBODY FAB FRAGMENT | Astellas Pharma Inc. (JP) | 2020-05-13 | — | — | EP | disclosed |