Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511451 | 0.89 | TAS2R38 (0.75) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL11751583 | 0.83 | ALDH1A1 (0.61) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL14501366 | 0.82 | EPHX1 (0.50) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL13693551 | 0.81 | MAPT (0.62) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL8705118 | 0.80 | GAA (0.65) | TAS2R38ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL863133 | 0.80 | TAS2R38 (0.62) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL11718858 | 0.78 | SMN1; SMN2 (0.67) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL21985779 | 0.78 | TAS2R38 (0.60) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL14872162 | 0.78 | TAS2R38 (0.60) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL10189868 | 0.78 | EPHX1 (0.60) | TAS2R38ALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |
| US-20130096177-A1 | POLYMERS FOR DELIVERING MOLECULES OF INTEREST | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096177-A1 | POLYMERS FOR DELIVERING MOLECULES OF INTEREST | PHAX, CD44, SNRPE | TAS2R38 4282/4885ALDH1A1 4494/4885GAA 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.