Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 6/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.38 |
| ▸ | PIK3R5 | Q8WYR1 | 6/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511634 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPTUSP2POLBPIN1 | |
| SCHEMBL14511647 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTUSP2PIN1LMNA | |
| SCHEMBL14511629 | 0.70 | MAPT (0.43) | ALDH1A1MAPTPIN1LMNAHTT | |
| SCHEMBL14511635 | 0.68 | RAB9A (0.50) | ALDH1A1PIN1LMNAHTTNPC1 | |
| SCHEMBL14511637 | 0.67 | PIN1 (0.50) | ALDH1A1MAPTPOLBPIN1LMNA | |
| SCHEMBL24018921 | 0.65 | HPGD (0.54) | ALDH1A1MAPTHTTPKMNPC1 | |
| SCHEMBL14511632 | 0.65 | MEN1 (0.44) | ALDH1A1MAPTPOLBPIN1NPC1 | |
| SCHEMBL8264513 | 0.61 | FGFR1 (0.55) | ALDH1A1MAPTHTTPKMSMN1; SMN2 | |
| SCHEMBL14736498 | 0.60 | PDE10A (0.51) | ALDH1A1PIN1LMNAHTTHTR2C | |
| SCHEMBL4375378 | 0.60 | HTT (0.40) | ALDH1A1MAPTUSP2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105900-A1 | Pharmaceutical compounds | ATEX THERAPEUTICS, LIMITED (GB) | 2007-05-10 | — | — | US | disclosed |
| US-20070105900-A1 | Pharmaceutical compounds | ATEX THERAPEUTICS, LIMITED (GB) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105900-A1 | Pharmaceutical compounds | AURKA, AURKC, CDK1 | ALDH1A1 1875/4885MAPT 1133/4885USP2 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.