Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511647 | 0.87 | ALDH1A1 (0.44) | ALDH1A1PIN1HTTUSP2MAPT | |
| SCHEMBL14511631 | 0.76 | ALDH1A1 (0.41) | ALDH1A1PIN1HTTPOLBUSP2 | |
| SCHEMBL14511629 | 0.74 | MAPT (0.43) | ALDH1A1PIN1HTTMAPTPKM | |
| SCHEMBL14511635 | 0.71 | RAB9A (0.50) | ALDH1A1PIN1HTTSMN1; SMN2LMNA | |
| SCHEMBL14511637 | 0.70 | PIN1 (0.50) | ALDH1A1PIN1HTTPOLBMAPT | |
| SCHEMBL14511632 | 0.69 | MEN1 (0.44) | ALDH1A1PIN1POLBMAPTSMN1; SMN2 | |
| SCHEMBL8264513 | 0.65 | FGFR1 (0.55) | ALDH1A1HTTHSP90AA1HSP90AB1MAPT | |
| SCHEMBL14803631 | 0.65 | HSP90AA1 (0.51) | ALDH1A1PIN1HSP90AA1HSP90AB1MAPT | |
| SCHEMBL12335793 | 0.64 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2GAASPR | |
| SCHEMBL14736498 | 0.64 | PDE10A (0.51) | ALDH1A1PIN1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105900-A1 | Pharmaceutical compounds | ATEX THERAPEUTICS, LIMITED (GB) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105900-A1 | Pharmaceutical compounds | AURKA, AURKC, CDK1 | ALDH1A1 1875/4885PIN1 705/4885HTT 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.