Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511632 | 0.80 | MEN1 (0.44) | RAB9ANPC1PIN1ALDH1A1EPHX2 | |
| SCHEMBL14705882 | 0.76 | HAO2 (0.44) | PIN1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL14511647 | 0.73 | ALDH1A1 (0.44) | L3MBTL1PIN1ALDH1A1LMNAHTT | |
| SCHEMBL14511640 | 0.72 | ALOX5 (0.51) | RAB9ANPC1ALDH1A1MAPK13MAPK12 | |
| SCHEMBL14705875 | 0.72 | SMN1; SMN2 (0.49) | RAB9ANPC1L3MBTL1ALDH1A1MAPK13 | |
| SCHEMBL8172365 | 0.71 | EPHX2 (0.71) | RAB9ANPC1L3MBTL1TSHREPHX2 | |
| SCHEMBL14511634 | 0.71 | ALDH1A1 (0.45) | L3MBTL1PIN1TSHRALDH1A1LMNA | |
| SCHEMBL14511637 | 0.70 | PIN1 (0.50) | L3MBTL1PIN1TSHRALDH1A1HPGD | |
| SCHEMBL5208543 | 0.69 | EPHX2 (0.77) | L3MBTL1TSHRALDH1A1EPHX2HPGD | |
| SCHEMBL7991747 | 0.69 | PARP1 (0.53) | L3MBTL1PIN1ALDH1A1MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105900-A1 | Pharmaceutical compounds | ATEX THERAPEUTICS, LIMITED (GB) | 2007-05-10 | — | — | US | disclosed |
| US-20070105900-A1 | Pharmaceutical compounds | ATEX THERAPEUTICS, LIMITED (GB) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105900-A1 | Pharmaceutical compounds | AURKA, AURKC, CDK1 | RAB9A 4050/4885NPC1 1220/4885L3MBTL1 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.