SCHEMBL145164

SCHEMBL145164

C=C(C)C(=O)OCC[SiH](OC)OC

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136943 0.89 TSHR (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL35127 0.87 TSHR (0.58) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28228114 0.85 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16207815 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16207723 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6381554 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL978174 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16207843 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16253927 0.82 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL5388463 0.82 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 679 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
EP-4649356-A1 UNDERLAYER AND METHODS FOR EUV LITHOGRAPHY Brewer Science, Inc. (US) 2025-11-19 EP claimed
WO-2025122886-A1 SYSTEMS FOR SUPERELASTIC SPLINES WITH POLYMER INSULATION ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. (US) 2025-06-12 WO claimed
WO-2024180279-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF PIBOND OY (FI) 2024-09-06 WO claimed
WO-2024173437-A1 UNDERLAYER AND METHODS FOR EUV LITHOGRAPHY BREWER SCIENCE, INC. (US) 2024-08-22 WO claimed
US-20240280905-A1 UNDERLAYER AND METHODS FOR EUV LITHOGRAPHY BREWER SCIENCE, INC. 2024-08-22 US claimed
US-12043738-B2 Silicone sealant having adjustable flow properties SIKA TECHNOLOGY AG (CH) 2024-07-23 US claimed
US-11975125-B2 Medical devices MICROVENTION, INC. (US) 2024-05-07 US claimed
EP-3860669-B1 MEDICAL DEVICES MICROVENTION INC (US) 2024-04-03 EP claimed
EP-1735369-B1 FAST CURING POLYDIORGANOSILOXANES HENKEL AG & CO KGAA (DE) 2008-12-03 EP claimed
EP-1940368-A2 TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION DOW CORNING CORPORATION (US) 2008-07-09 EP claimed
WO-2007050580-A2 TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION DOW CORNING CORPORATION (US) 2007-05-03 WO claimed
EP-1735369-A1 FAST CURING POLYDIORGANOSILOXANES Henkel Kommanditgesellschaft auf Aktien (DE) 2006-12-27 EP claimed
US-20060257673-A1 Laminates, their production and use CELANESE EMULSIONS GMBH (DE) 2006-11-16 US claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
WO-2005100446-A1 FAST CURING POLYDIORGANOSILOXANES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-10-27 WO claimed
US-20050234208-A1 Fast curing polydiorganosiloxanes HENKEL AG & CO. KGAA (DE) 2005-10-20 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 THRB 4533/4885TSHR 4650/4885ALDH1A1 402/4885
US-20240280905-A1 UNDERLAYER AND METHODS FOR EUV LITHOGRAPHY ETV6, EPHA4, EPHA6 THRB 4814/4885TSHR 4851/4885ALDH1A1 4678/4885
US-20260118766-A1 Silicon containing coating compositions and uses thereof ITGA8, SMCHD1, GCN1 THRB 477/4885TSHR 957/4885ALDH1A1 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.