Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 4/20 | 0.44 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819846 | 0.91 | PPM1B (0.56) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL16675540 | 0.91 | PPM1B (0.56) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL9880145 | 0.91 | PPM1B (0.56) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL11393084 | 0.74 | PPM1B (0.61) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL1005051 | 0.74 | PPM1B (0.61) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL13480836 | 0.74 | PPM1B (0.61) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL6778458 | 0.74 | PPM1B (0.61) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL9697481 | 0.74 | PPM1B (0.61) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL13897079 | 0.74 | PPM1B (0.61) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL12762660 | 0.72 | PPM1B (0.39) | PPM1BALDH1A1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264593-A1 | PROTEIN PHOSPHATASE INHIBITORS THAT CROSS THE BLOOD BRAIN BARRIER | LIXTE BIOTECHNOLOGY, INC. | 2016-09-15 | — | — | US | disclosed |
| US-7202016-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2007-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264593-A1 | PROTEIN PHOSPHATASE INHIBITORS THAT CROSS THE BLOOD BRAIN BARRIER | DUSP1, PPP5C, DUSP15 | PPM1B 42/4885FUCA1 388/4885ALDH1A1 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.