Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546813 | 0.81 | KEAP1 (0.41) | ALDH1A1KDM4EMEN1KMT2AKEAP1 | |
| SCHEMBL7541835 | 0.74 | MEN1 (0.40) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10147792 | 0.69 | CA1 (0.33) | — | |
| SCHEMBL28386898 | 0.69 | KEAP1 (0.47) | KEAP1NFE2L2MAPTCHRM2CHRM1 | |
| Toluene SCHEMBL28194530 | 0.68 | LMNA (0.44) | ALDH1A1KDM4EMEN1KMT2AUSP2 | |
| SCHEMBL776895 | 0.67 | MAPT (0.55) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL27432645 | 0.67 | KEAP1 (0.48) | KEAP1NFE2L2CYP2B6MAPTCHRM2 | |
| SCHEMBL846064 | 0.67 | KEAP1 (0.48) | KEAP1NFE2L2CYP2B6MAPTCHRM2 | |
| SCHEMBL12364132 | 0.67 | — | — | |
| SCHEMBL6878670 | 0.67 | CES1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202016-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2007-04-10 | — | — | US | disclosed |
| US-7202016-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2007-04-10 | — | — | US | disclosed |