SCHEMBL10147792

SCHEMBL10147792

CC(C)(C)S(=O)(=O)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.33
CA12 O43570 2/20 0.33
CA7 P43166 2/20 0.33
CA14 Q9ULX7 2/20 0.33
EPHX2 P34913 1/20 0.32
CA2 P00918 2/20 0.31
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12364132 0.97
SCHEMBL491156 0.92 ACHE (0.32)
SCHEMBL9944453 0.86
SCHEMBL1697213 0.80 PDK1 (0.33) CA1CA12CA7CA14
SCHEMBL10146064 0.80 CA12 (0.31) CA1CA12CA7CA14
SCHEMBL14227526 0.77
SCHEMBL14241860 0.77 CYP1A2 (0.32)
SCHEMBL14667211 0.75 CNR2 (0.38)
SCHEMBL10171127 0.75 ADH1B (0.30)
SCHEMBL7783201 0.75 CA12 (0.31) CA1CA12CA7CA14EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230057401-A1 COATED UNDERLAYER FOR OVERCOATED PHOTORESIST U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-02-23 US disclosed
US-11236111-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2022-02-01 US disclosed
US-10894777-B2 TG2 inhibitor piperazine compounds and uses thereof UNIVERSITY OF OTTAWA (CA) 2021-01-19 US disclosed
US-20200377519-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2020-12-03 US disclosed
US-20200317678-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARM INC (US) 2020-10-08 US disclosed
US-10723733-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2020-07-28 US disclosed
US-10689409-B2 Amino compounds for treatment of complement mediated disorders ACHILLION PHARMACEUTICALS, INC. (US) 2020-06-23 US disclosed
US-10640511-B2 Hepatitis B antiviral agents Enant Pharmaceuticals, Inc. (US) 2020-05-05 US disclosed
US-10428070-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2019-10-01 US disclosed
US-20190177320-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2019-06-13 US disclosed
US-20170355701-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2017-12-14 US disclosed
US-20170189410-A1 Amino Compounds for Treatment of Complement Mediated Disorders ACHILLION PHARMACEUTICALS, INC. (US) 2017-07-06 US disclosed
US-9598446-B2 Amino compounds for treatment of complement mediated disorders ACHILLION PHARMACEUTICALS, INC. (US) 2017-03-21 US disclosed
US-20170073334-A1 SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-03-16 US disclosed
US-20160332999-A1 HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME EA PHARMA CO., LTD. (JP) 2016-11-17 US disclosed
US-9365523-B2 Imidazolyl amide compounds and uses related thereto EMORY UNIVERSITY (US) 2016-06-14 US disclosed
US-9315454-B2 Compounds which modulate the CB2 receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2016-04-19 US disclosed
US-20150239894-A1 Amino Compounds for Treatment of Complement Mediated Disorders ACHILLION PHARMACEUTICALS, INC. (US) 2015-08-27 US disclosed
US-20140080828-A1 IMIDAZOLYL AMIDE COMPOUNDS AND USES RELATED THERETO CHILDREN'S HEATLHCARE OF ATLANTA, INC. (US) 2014-03-20 US disclosed
EP-2418207-A1 Sulfone compounds which modulate the CB2 receptor Boehringer Ingelheim International GmbH (DE) 2012-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140080828-A1 IMIDAZOLYL AMIDE COMPOUNDS AND USES RELATED THERETO TPMT, PNP, MTAP CA1 3743/4885CA12 4026/4885CA7 1293/4885
US-11236111-B2 Hepatitis B antiviral agents HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-20160332999-A1 HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME TRPA1, TRPV1, TRPV2 CA1 1394/4885CA12 2393/4885CA7 2046/4885
US-20170073334-A1 SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE PRKACA, PRKDC, PRKACB CA1 4866/4885CA12 4801/4885CA7 4612/4885
US-20200317678-A1 HEPATITIS B ANTIVIRAL AGENTS HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-20190177320-A1 HEPATITIS B ANTIVIRAL AGENTS HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-10428070-B2 Hepatitis B antiviral agents HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-20200377519-A1 HEPATITIS B ANTIVIRAL AGENTS HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-20150239894-A1 Amino Compounds for Treatment of Complement Mediated Disorders CFD, TFPI, C9 CA1 2728/4885CA12 1636/4885CA7 4558/4885
US-20170355701-A1 HEPATITIS B ANTIVIRAL AGENTS HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-10723733-B2 Hepatitis B antiviral agents HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-10894777-B2 TG2 inhibitor piperazine compounds and uses thereof TGM2, TGM1, TGM3 CA1 854/4885CA12 2544/4885CA7 2139/4885
US-10689409-B2 Amino compounds for treatment of complement mediated disorders CFD, TFPI, C9 CA1 2728/4885CA12 1636/4885CA7 4558/4885
US-10640511-B2 Hepatitis B antiviral agents HAVCR2, SLC10A1, HDGF CA1 3742/4885CA12 2997/4885CA7 3147/4885
US-20170189410-A1 Amino Compounds for Treatment of Complement Mediated Disorders CFD, TFPI, C9 CA1 2728/4885CA12 1636/4885CA7 4558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.