Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811989 | 0.84 | SIGMAR1 (0.38) | ALDH1A1HTTHPGDGAAMAPK1 | |
| SCHEMBL14994305 | 0.81 | SIGMAR1 (0.37) | ALDH1A1HTTHPGDGAAMAPK1 | |
| SCHEMBL14532929 | 0.80 | PTPN1 (0.44) | HPGDALOX15ALOX12SMN1; SMN2CYP3A4 | |
| SCHEMBL27351642 | 0.78 | TRPA1 (0.45) | ALDH1A1HPGDGAAALOX15ALOX12 | |
| Acetic Acid SCHEMBL20740116 | 0.78 | GPR35 (0.41) | ALDH1A1HPGDSIGMAR1MAPTTSHR | |
| SCHEMBL11311046 | 0.78 | ALOX15 (0.41) | ACLYALDH1A1HTTHPGDGAA | |
| SCHEMBL11038722 | 0.78 | SELL (0.58) | ACLYALDH1A1HPGDGAAMAPK1 | |
| SCHEMBL21120986 | 0.77 | TSHR (0.43) | ALDH1A1HTTHPGDALOX15SIGMAR1 | |
| SCHEMBL5680640 | 0.77 | SELL (0.59) | ALDH1A1HTTHPGDGAAMAPK1 | |
| SCHEMBL30686944 | 0.77 | ACHE (0.59) | ALDH1A1HTTHPGDGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |