Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510113 | 0.77 | ACP1 (0.56) | ALDH1A1ACP1L3MBTL1FABP4KMT2A | |
| SCHEMBL6927414 | 0.76 | KDM1A (0.54) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL11879620 | 0.76 | IDO1 (0.52) | ALDH1A1ACP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL14461328 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ACP1L3MBTL1FABP4KMT2A | |
| SCHEMBL16444001 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ACP1L3MBTL1FABP4KMT2A | |
| SCHEMBL14462109 | 0.74 | ACP1 (0.58) | ALDH1A1ACP1L3MBTL1FABP4KMT2A | |
| SCHEMBL1324419 | 0.74 | L3MBTL1 (0.65) | ALDH1A1ACP1L3MBTL1FABP4KMT2A | |
| SCHEMBL5453827 | 0.73 | BCHE (0.51) | ALDH1A1L3MBTL1RAB9AHSD17B10HTT | |
| SCHEMBL4008576 | 0.72 | ACP1 (0.59) | ALDH1A1ACP1L3MBTL1FABP4KMT2A | |
| SCHEMBL27182678 | 0.72 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | ADRB2, ADRB1, CHRNA7 | ALDH1A1 627/4885ACP1 4223/4885L3MBTL1 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.