Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.42 |
| ▸ | MICA | Q29983 | 2/20 | 0.42 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307353 | 0.79 | KEAP1 (0.50) | KEAP1NFE2L2SMN1; SMN2MAPTSMO | |
| SCHEMBL6368500 | 0.76 | MMP12 (1.00) | MMP12MMP13IGF2BP2SUCNR1 | |
| SCHEMBL6141835 | 0.76 | MMP12 (1.00) | MMP12MMP13IGF2BP2SUCNR1 | |
| SCHEMBL6141848 | 0.76 | MMP12 (1.00) | MMP12MMP13IGF2BP2SUCNR1 | |
| SCHEMBL1308440 | 0.73 | KLRK1 (0.53) | KEAP1NFE2L2KLRK1MICARAET1L | |
| Triflumuron SCHEMBL23700 | 0.70 | TDP1 (1.00) | TDP1KDM4ESMN1; SMN2MAPT | |
| Triflumuron SCHEMBL9490691 | 0.70 | TDP1 (1.00) | TDP1KDM4ESMN1; SMN2MAPT | |
| Triflumuron SCHEMBL29832813 | 0.70 | TDP1 (1.00) | TDP1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8299843 | 0.70 | SMN1; SMN2 (0.48) | KDM4ESMN1; SMN2MAPT | |
| SCHEMBL3646792 | 0.69 | CTSS (0.50) | MMP12MMP13TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322608-B1 | DELTA1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-02 | — | — | EP | disclosed |