Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 10/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.59 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.59 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492855 | 0.84 | NPC1 (0.68) | L3MBTL1TDP1NPC1KDM4EPTPN1 | |
| SCHEMBL29467270 | 0.84 | NPC1 (0.68) | L3MBTL1TDP1NPC1KDM4EPTPN1 | |
| SCHEMBL227731 | 0.82 | NPC1 (0.71) | L3MBTL1NPC1KDM4EPTPN1 | |
| SCHEMBL1715918 | 0.82 | NPC1 (0.71) | L3MBTL1NPC1KDM4EPTPN1 | |
| SCHEMBL722824 | 0.82 | L3MBTL1 (0.63) | L3MBTL3L3MBTL1TP53BP1MBTD1MEN1 | |
| SCHEMBL6829549 | 0.81 | NOTUM (0.51) | L3MBTL1TDP1NPC1PTPN1 | |
| SCHEMBL27676401 | 0.81 | ALDH1A1 (0.48) | L3MBTL1TDP1NPC1PTPN1 | |
| SCHEMBL15533384 | 0.81 | ALDH1A1 (0.48) | L3MBTL1TDP1KMT2ANPC1PTPN1 | |
| SCHEMBL8048603 | 0.80 | ALDH1A1 (0.61) | L3MBTL1TDP1MEN1KMT2ANPC1 | |
| SCHEMBL6650052 | 0.80 | KMT2A (0.60) | L3MBTL1TDP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053498-A1 | COMPOUNDS USEFUL AS ANTAGONISTS OF CCR2 | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-05-10 | — | — | WO | disclosed |