Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427614 | 0.86 | TP53 (0.38) | CASP7CASP6KMT2AQPCTSIGMAR1 | |
| SCHEMBL427421 | 0.70 | GRM4 (0.47) | KMT2ASIGMAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL13758989 | 0.69 | HTT (0.52) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL13759248 | 0.68 | MAPK14 (0.49) | SMN1; SMN2 | |
| SCHEMBL13759001 | 0.67 | KDR (0.49) | ALDH1A1 | |
| SCHEMBL14530047 | 0.66 | FLT3 (0.41) | — | |
| SCHEMBL13759253 | 0.66 | KDR (0.46) | CRHR1MAPK1 | |
| SCHEMBL13758992 | 0.65 | FLT3 (0.41) | RAB9A | |
| SCHEMBL13759251 | 0.65 | MAPK14 (0.51) | CRHR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL14412478 | 0.65 | CRHR1 (0.44) | CRHR1CASP7CASP6SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050980-A2 | PROCESS FOR PREPARING MESYLATE SALTS OF IL-12 INHIBITORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2007-05-03 | — | — | WO | disclosed |