Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | HSD17B14 | Q9BPX1 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515798 | 0.86 | MAPT (0.61) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL10351730 | 0.84 | MAPT (0.58) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL10350541 | 0.82 | RAB9A (0.56) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL27955217 | 0.82 | MAPT (0.56) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL1515818 | 0.82 | L3MBTL1 (0.65) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL1515782 | 0.79 | MAPT (0.60) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL4969713 | 0.79 | MAPT (0.51) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL27707508 | 0.78 | ALB (0.44) | MAPTHSD17B14NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL760057 | 0.78 | SMN1; SMN2 (0.52) | MAPTL3MBTL1SRD5A2RAB9ANPC1 | |
| SCHEMBL7129800 | 0.78 | MAPT (0.80) | MAPTL3MBTL1SRD5A2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062308-A2 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |