Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 6/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.39 |
| ▸ | PI4KA | P42356 | 10/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 10/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.39 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14536831 | 0.85 | AURKA (0.46) | AURKAAURKBSYKTTKPTK6 | |
| SCHEMBL14536853 | 0.81 | AURKA (0.46) | AURKAAURKBTTKPTK6 | |
| SCHEMBL14537040 | 0.81 | AURKA (0.48) | AURKAAURKBTTKPTK6 | |
| SCHEMBL8240268 | 0.80 | AURKA (0.58) | AURKAAURKBPIK3CDPI4KAPIK3CG | |
| SCHEMBL14530183 | 0.79 | AURKA (0.45) | AURKAAURKBTTKPTK6 | |
| SCHEMBL14536959 | 0.78 | TTK (0.54) | AURKAAURKBTTK | |
| SCHEMBL14530182 | 0.78 | AURKA (0.53) | AURKAAURKBTTK | |
| SCHEMBL14537044 | 0.77 | AURKA (0.45) | AURKAAURKBSYKTTKPTK6 | |
| SCHEMBL13954838 | 0.76 | AURKA (0.45) | AURKAAURKBTTKPTK6 | |
| SCHEMBL14537007 | 0.75 | AURKA (0.48) | AURKAAURKBTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056468-A1 | METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |