Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965064 | 0.90 | REN (0.34) | RENKCNH2PKMCNR2CNR1 | |
| SCHEMBL4962193 | 0.87 | PKM (0.36) | RENKCNH2PKMMEN1MAPT | |
| SCHEMBL4964833 | 0.86 | HDAC1 (0.35) | RENKCNH2PKMMEN1MAPT | |
| SCHEMBL4962151 | 0.86 | HTR2A (0.37) | RENKCNH2PKMPDE1BMEN1 | |
| SCHEMBL14541851 | 0.83 | RXFP1 (0.33) | KCNH2PKMCNR2CNR1MEN1 | |
| SCHEMBL4962762 | 0.82 | P2RX7 (0.33) | RENKCNH2PKMMEN1MAPT | |
| SCHEMBL4963385 | 0.82 | MEN1 (0.36) | PKMMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4966274 | 0.81 | P2RX7 (0.33) | RENKCNH2PKMMEN1MAPT | |
| SCHEMBL4962815 | 0.81 | LMNA (0.33) | RENKCNH2PKMCNR2CNR1 | |
| SCHEMBL4965046 | 0.81 | HTR6 (0.37) | PKMMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042883-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER PRODUCTS INC. (US) | 2007-04-19 | — | — | WO | disclosed |