Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954782 | 0.84 | ALDH1A1 (0.37) | PDGFRBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5769612 | 0.83 | ALDH1A1 (0.36) | PDGFRBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5358334 | 0.83 | ALDH1A1 (0.39) | PDGFRBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29954578 | 0.79 | ALDH1A1 (0.34) | PDGFRBALDH1A1POLBKMT2AIGF1R | |
| SCHEMBL9735543 | 0.79 | IGF1R (0.37) | ALDH1A1POLBKMT2AIGF1R | |
| SCHEMBL12849434 | 0.77 | HSD17B10 (0.36) | PDGFRBALDH1A1POLBKMT2AIGF1R | |
| SCHEMBL10810611 | 0.76 | ALDH1A1 (0.34) | CYP1A2CYP2C9CYP2C19ALDH1A1POLB | |
| SCHEMBL15380984 | 0.74 | ALDH1A1 (0.36) | CYP1A2CYP2C9CYP2C19ALDH1A1POLB | |
| SCHEMBL14560302 | 0.74 | FGFR1 (0.42) | PDGFRBHSD17B10 | |
| SCHEMBL25295408 | 0.72 | SMN1; SMN2 (0.58) | CYP1A2CYP2C9CYP2C19ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20220031870-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | UNIVERSITY OF SOUTHAMPTON (GB) | 2022-02-03 | — | — | US | disclosed |
| EP-2991969-B1 | METAL COMPLEXES AND FLUORINATION THEREOF | GE HEALTHCARE LTD (GB) | 2020-04-01 | — | — | EP | disclosed |
| CN-105324367-B | Metal complexes and fluorination thereof | 通用电气健康护理有限公司 | 2018-11-02 | — | — | CN | disclosed |
| US-20160082136-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | UNIVERSITY OF SOUTHAMPTON (GB) | 2016-03-24 | — | — | US | disclosed |
| US-20160074540-A1 | METAL COMPLEXES AND THEIR FLUORINATION | UNIVERSITY OF SOUTHAMPTON (GB) | 2016-03-17 | — | — | US | disclosed |
| EP-2991688-A1 | METAL COMPLEXES AND THEIR FLUORINATION | GE Healthcare UK Limited (GB) | 2016-03-09 | — | — | EP | disclosed |
| EP-2991969-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | GE Healthcare UK Limited (GB) | 2016-03-09 | — | — | EP | disclosed |
| CN-105339013-A | Metal complexes and fluorination thereof | GE HEALTHCARE LTD | 2016-02-17 | — | — | CN | disclosed |
| CN-105324367-A | Metal complexes and fluorination thereof | GE HEALTHCARE LTD | 2016-02-10 | — | — | CN | disclosed |
| WO-2014177690-A1 | METAL COMPLEXES AND THEIR FLUORINATION | GE HEALTHCARE LIMITED (GB) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014177689-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | GE HEALTHCARE LIMITED (GB) | 2014-11-06 | — | — | WO | disclosed |
| US-7202265-B2 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. (US) | 2007-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074540-A1 | METAL COMPLEXES AND THEIR FLUORINATION | FOS, FOSB, AFF1 | PDGFRB 759/4885CYP1A2 2374/4885CYP2C9 1563/4885 |
| US-20220031870-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | FOS, FGB, FOSB | PDGFRB 919/4885CYP1A2 2639/4885CYP2C9 1570/4885 |
| US-20160082136-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | FOS, FGB, FOSB | PDGFRB 843/4885CYP1A2 2467/4885CYP2C9 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.