Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129150 | 0.82 | ABL1 (0.47) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL9129147 | 0.82 | ABL1 (0.47) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL14544483 | 0.81 | LMNA (0.46) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL12566880 | 0.81 | CYP1A2 (0.35) | ALDH1A1LMNAALBMAPK1PRMT5 | |
| SCHEMBL14149657 | 0.77 | ALDH1A1 (0.53) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL8783994 | 0.77 | ALDH1A1 (0.53) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL9128530 | 0.77 | ABL1 (0.45) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL9128537 | 0.77 | ABL1 (0.45) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL23982434 | 0.77 | ADK (0.51) | ALDH1A1LMNAALBMAPK1PRMT5 | |
| SCHEMBL20916985 | 0.77 | PRMT5 (0.45) | PRMT5WDR77ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202224-B2 | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase | MERCK & CO., INC. (US) | 2007-04-10 | — | — | US | disclosed |