Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | CD40 | P25942 | 1/20 | 0.34 |
| ▸ | CD40LG | P29965 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.32 |
| ▸ | P2RX5 | Q93086 | 2/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546742 | 0.94 | ENPP2 (0.42) | ENPP2AMY1ACA2CA3THRB | |
| SCHEMBL14546979 | 0.90 | ENPP2 (0.43) | ENPP2AMY1ACA2CA3THRB | |
| SCHEMBL14546913 | 0.87 | THRB (0.42) | ENPP2AMY1ACA2THRBCD40 | |
| SCHEMBL14546978 | 0.85 | ENPP2 (0.51) | ENPP2AMY1ACA2CA3THRB | |
| SCHEMBL14547005 | 0.84 | ENPP2 (0.51) | ENPP2AMY1ACA2CA3THRB | |
| SCHEMBL12053238 | 0.82 | ENPP2 (0.44) | ENPP2AMY1ACA2CA3THRB | |
| SCHEMBL14546744 | 0.82 | P2RX5 (0.38) | ENPP2THRBCD40CD40LGRPS6KA3 | |
| SCHEMBL14546917 | 0.81 | ENPP2 (0.49) | ENPP2AMY1ACA2CA3THRB | |
| SCHEMBL14546741 | 0.80 | THRB (0.45) | ENPP2AMY1ATHRBRPS6KA3ATIC | |
| SCHEMBL12053136 | 0.78 | ENPP2 (0.44) | ENPP2AMY1ACA2CA3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |