Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634802 | 0.86 | — | — | |
| SCHEMBL12330836 | 0.69 | — | — | |
| SCHEMBL1255910 | 0.67 | ALDH1A1 (0.57) | MIFALDH1A1BCHEPOLBMAOA | |
| Benzoquinone SCHEMBL29080995 | 0.67 | ALDH1A1 (0.57) | MIFALDH1A1BCHEPOLBMAOA | |
| SCHEMBL7093744 | 0.66 | ALDH1A1 (0.33) | ALDH1A1MAPK1IDO1 | |
| Benzoquinone SCHEMBL28597092 | 0.65 | ALDH1A1 (0.80) | MIFALDH1A1BCHEPOLBMAOA | |
| SCHEMBL11345168 | 0.65 | — | — | |
| Benzoquinone SCHEMBL460082 | 0.65 | ALDH1A1 (1.00) | MIFALDH1A1BCHEPOLBMAOA | |
| Benzoquinone SCHEMBL18103 | 0.65 | — | — | |
| Benzoquinone SCHEMBL10506648 | 0.65 | ALDH1A1 (1.00) | MIFALDH1A1BCHEPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796489-B2 | Ketobenzofuran derivatives, method for synthesizing same, and intermediates | SANOFI (FR) | 2014-08-05 | — | — | US | disclosed |
| US-8796489-B2 | Ketobenzofuran derivatives, method for synthesizing same, and intermediates | SANOFI (FR) | 2014-08-05 | — | — | US | disclosed |
| US-20130012729-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES | SANOFI (FR) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012729-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES | NNMT, DHPS, NDUFC1 | MIF 4191/4885ALDH1A1 377/4885BCHE 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.