Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14552323 | 0.88 | SOAT1 (0.48) | SOAT1TRPM8FAAHCNR2HDAC3 | |
| SCHEMBL17914102 | 0.86 | SOAT1 (0.47) | SOAT1TRPM8FAAHCNR2HDAC3 | |
| SCHEMBL14552512 | 0.85 | TRPM8 (0.49) | TRPM8HDAC3HDAC1HDAC6HPGD | |
| SCHEMBL14552385 | 0.76 | SOAT1 (0.56) | SOAT1TRPM8FAAHCNR2HDAC3 | |
| SCHEMBL9955679 | 0.74 | CYP3A4 (0.55) | TRPM8HDAC3HDAC1HDAC6HPGD | |
| SCHEMBL5718458 | 0.74 | FAAH (0.56) | SOAT1TRPM8FAAHCNR2HDAC3 | |
| SCHEMBL28811157 | 0.74 | FAAH (0.56) | SOAT1TRPM8FAAHCNR2HDAC3 | |
| SCHEMBL8392526 | 0.74 | FAAH (0.56) | SOAT1TRPM8FAAHCNR2HDAC3 | |
| SCHEMBL8393161 | 0.74 | FAAH (0.56) | SOAT1TRPM8FAAHCNR2HDAC3 | |
| SCHEMBL9955675 | 0.74 | CYP3A4 (0.55) | TRPM8HDAC3HDAC1HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9386767-B2 | Derivatives of dillapiol and related monolignans and use thereof | UNIVERSITY OF OTTAWA (CA) | 2016-07-12 | — | — | US | disclosed |
| US-9386767-B2 | Derivatives of dillapiol and related monolignans and use thereof | UNIVERSITY OF OTTAWA (CA) | 2016-07-12 | — | — | US | disclosed |
| US-20130012477-A1 | DERIVATIVES OF DILLAPIOL AND RELATED MONOLIGNANS AND USE THEREOF | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF HEALTH (CA) | 2013-01-10 | — | — | US | disclosed |
| US-20130012477-A1 | DERIVATIVES OF DILLAPIOL AND RELATED MONOLIGNANS AND USE THEREOF | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF HEALTH (CA) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012477-A1 | DERIVATIVES OF DILLAPIOL AND RELATED MONOLIGNANS AND USE THEREOF | CYP3A43, CYP3A4, CYP4A22 | SOAT1 453/4885TRPM8 457/4885FAAH 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.