Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454933 | 1.00 | PTPN1 (0.40) | PTPN1LMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL25203489 | 0.96 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL1453540 | 0.96 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL1455188 | 0.87 | PTPN1 (0.40) | PTPN1LMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL1904998 | 0.84 | LMNA (0.56) | PTPN1LMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL4509621 | 0.84 | LMNA (0.56) | PTPN1LMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL4507632 | 0.84 | LMNA (0.56) | PTPN1LMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL1453728 | 0.84 | PTPN1 (0.37) | PTPN1LMNA | |
| SCHEMBL1906086 | 0.83 | PTPN1 (0.40) | PTPN1LMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL9621897 | 0.81 | ACE2 (0.46) | PTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910617-B2 | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound | SANKYO COMPANY, LIMITED (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20070191468-A1 | Amino alcohol compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1733724-A1 | AMINO ALCOHOL COMPOUND | Sankyo Company, Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191468-A1 | Amino alcohol compound | ADH1A, ADH1C, BCAT1 | PTPN1 2147/4885LMNA 3709/4885MEN1 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.