SCHEMBL4507632

SCHEMBL4507632

C=C(C)CCCC(C)CCCC(C)CCCC(C)C

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
PTPN1 P18031 4/20 0.55
BLM P54132 1/20 0.47
MEN1 O00255 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX15 P16050 1/20 0.46
KMT2A Q03164 1/20 0.46
PTGS1 P23219 1/20 0.36
PDE4A P27815 1/20 0.36
SNCA P37840 1/20 0.36
PDE3A Q14432 1/20 0.36
KDM1A O60341 1/20 0.33
PTPN2 P17706 2/20 0.32
CDC25B P30305 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1904998 1.00 LMNA (0.56) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL4509621 1.00 LMNA (0.56) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL3696275 0.93 LMNA (0.61) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL11683165 0.93 LMNA (0.61) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL11681508 0.91 LMNA (0.56) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL1296360 0.91
Bromide SCHEMBL28303227 0.88 PTPN1 (0.41) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL1455243 0.84 PTPN1 (0.40) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL1455188 0.84 PTPN1 (0.40) LMNAPTPN1BLMMEN1CYP3A4
SCHEMBL1906086 0.84 PTPN1 (0.40) LMNAPTPN1BLMMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11724996-B2 Synthesis of intermediates for the preparation of alpha-tocopherol DSM IP ASSETS B.V. (NL) 2023-08-15 US disclosed
EP-3652162-B1 NOVEL SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL DSM IP ASSETS BV (NL) 2023-02-22 EP disclosed
WO-2023016459-A1 NOVEL ORGANIC ALKOXIDE AGGLOMERATE, AND PREPARATION METHOD THEREFOR AND APPLICATION AND THEREOF 上海科技大学 2023-02-16 WO disclosed
US-11471533-B2 Compound usable as cationic lipid KYOWA KIRIN CO., LTD. (JP) 2022-10-18 US disclosed
EP-3521270-B1 CATIONIC LIPID COMPOUND KYOWA KIRIN CO LTD (JP) 2022-06-29 EP disclosed
WO-2021238947-A1 METHOD FOR PREPARING QUINONE COMPOUND 上海科技大学 2021-12-02 WO disclosed
US-20210300886-A1 SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL DSM IP ASSETS BV (NL) 2021-09-30 US disclosed
US-20210275672-A1 COMPOUND USABLE AS CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2021-09-09 US disclosed
US-20200131145-A1 NOVEL SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL DSM IP ASSETS B.V. (NL) 2020-04-30 US disclosed
EP-3521270-A1 CATIONIC LIPID COMPOUND Kyowa Hakko Kirin Co., Ltd. (JP) 2019-08-07 EP disclosed
US-6133471-A Process for producing chromans KURARAY CO., LTD. (JP) 2000-10-17 US disclosed
US-6130341-A Process for producing chromans KURARAY CO., LTD. (JP) 2000-10-10 US disclosed
EP-0645383-B1 Process for producing chromanes KURARAY CO (JP) 1999-03-24 EP disclosed
EP-0891974-A1 Process for producing chromans KURARAY CO., LTD. (JP) 1999-01-20 EP disclosed
US-5495026-A Process for producing chroman KURARAY COMPANY LTD. (JP) 1996-02-27 US disclosed
EP-0645383-A1 Process for producing chroman KURARAY CO., LTD. (JP) 1995-03-29 EP disclosed
EP-0310005-B1 Process for modifying the microbial cleansing of soil contaminated with hydrocarbons, in particular with mineral oils, by microbial oxidation WINTERSHALL AG (DE) 1993-11-24 EP disclosed
US-4888275-A DETERMINATION OF CARBOHYDRATE ANTIGEN PHARMACIA AB, S-751 82 UPPSALA (CH) 1989-12-19 US disclosed
EP-0310005-A1 Process for modifying the microbial cleansing of soil contaminated with hydrocarbons, in particular with mineral oils, by microbial oxidation WINTERSHALL AKTIENGESELLSCHAFT (DE) 1989-04-05 EP disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210300886-A1 SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL TTPA, DHPS, SQLE LMNA 1425/4885PTPN1 4639/4885BLM 3409/4885
US-20200131145-A1 NOVEL SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL TTPA, VKORC1, SQLE LMNA 1413/4885PTPN1 4761/4885BLM 3636/4885
US-11471533-B2 Compound usable as cationic lipid NPC1L1, PLIN1, PLIN5 LMNA 278/4885PTPN1 4533/4885BLM 1287/4885
US-11724996-B2 Synthesis of intermediates for the preparation of alpha-tocopherol TTPA, DHPS, SQLE LMNA 1425/4885PTPN1 4639/4885BLM 3409/4885
US-20210275672-A1 COMPOUND USABLE AS CATIONIC LIPID NPC1L1, PLIN1, PLIN5 LMNA 278/4885PTPN1 4533/4885BLM 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.