Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 15/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701249 | 0.88 | OPRM1 (0.51) | OPRK1OPRM1OPRD1KCNH2GAA | |
| SCHEMBL4699788 | 0.87 | OPRM1 (0.67) | OPRK1OPRM1OPRD1KCNH2 | |
| SCHEMBL14564788 | 0.86 | LMNA (0.43) | OPRK1OPRM1OPRD1KCNH2 | |
| SCHEMBL14564782 | 0.83 | LMNA (0.38) | OPRK1OPRM1OPRD1KCNH2 | |
| SCHEMBL14564786 | 0.83 | FUCA1 (0.40) | OPRK1OPRM1OPRD1KCNH2 | |
| SCHEMBL14564781 | 0.81 | LMNA (0.39) | OPRK1OPRM1OPRD1KCNH2 | |
| SCHEMBL14564787 | 0.79 | SIGMAR1 (0.43) | — | |
| SCHEMBL4698332 | 0.78 | OPRM1 (0.58) | OPRK1OPRM1OPRD1KCNH2 | |
| SCHEMBL4702121 | 0.75 | OPRM1 (0.45) | OPRK1OPRM1OPRD1KCNH2 | |
| SCHEMBL4698357 | 0.75 | LMNA (0.42) | OPRK1OPRM1OPRD1KCNH2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054950-A1 | 3-Azabicyclo[3.1.0]hexane derivatives | PFIZER INC. | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054950-A1 | 3-Azabicyclo[3.1.0]hexane derivatives | OPRD1, OPRM1, OPRK1 | OPRK1 3/4885OPRM1 2/4885OPRD1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.