Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905327 | 0.83 | GRM2 (0.49) | GRM2ALDH1A1DHODHKDM4EMAPT | |
| SCHEMBL3332188 | 0.79 | ALDH1A1 (0.50) | GRM2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL2907089 | 0.79 | GRM2 (0.46) | GRM2ALDH1A1LMNAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3330671 | 0.78 | GRM2 (0.45) | GRM2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL3638273 | 0.74 | GRM2 (0.43) | GRM2ALDH1A1DHODHKDM4EMAPT | |
| SCHEMBL6593684 | 0.73 | CYP1A2 (0.50) | GRM2ALDH1A1LMNADHODHKDM4E | |
| SCHEMBL15978468 | 0.73 | TRPA1 (0.41) | GRM2ALDH1A1LMNADHODHKDM4E | |
| SCHEMBL27775230 | 0.73 | MAPT (0.44) | GRM2ALDH1A1LMNADHODHKDM4E | |
| SCHEMBL14392924 | 0.72 | GPR35 (0.44) | LMNAKDM4EMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27795960 | 0.72 | MAPT (0.43) | GRM2ALDH1A1LMNADHODHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474441-B1 | TRIPEPTIDES HAVING A HYDROXYPROLINE ETHER OF A SUBSTITUTED QUINOLINE FOR THE INHIBITION OF NS3 (HEPATITIS C) | BOEHRINGER INGELHEIM INT (DE) | 2007-03-28 | — | — | EP | disclosed |