Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.64 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.64 |
| ▸ | ITGAL | P20701 | 6/20 | 0.64 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.63 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805861 | 1.00 | ITGB2 (0.64) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL10670546 | 0.87 | ITGB2 (0.63) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL10670547 | 0.87 | ITGB2 (0.63) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL9828348 | 0.87 | ERAP2 (0.74) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL9828342 | 0.87 | ERAP2 (0.74) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL5259129 | 0.87 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL30616778 | 0.87 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL9466705 | 0.87 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL5191302 | 0.87 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL15145406 | 0.86 | ITGB2 (0.63) | ITGB2ICAM1ITGALERAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593144-B2 | FPR1 antagonist derivatives and use thereof | CHANG GUNG UNIVERSITY (TW) | 2017-03-14 | — | — | US | disclosed |
| US-20150307548-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | CHANG GUNG UNIVERSITY (TW) | 2015-10-29 | — | — | US | disclosed |
| US-20150099691-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | CHANG GUNG UNIVERSITY (TW) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307548-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | FPR1, FPR3, FPR2 | ITGB2 3304/4885ICAM1 1315/4885ITGAL 3019/4885 |
| US-20150099691-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | FPR1, FPR3, FPR2 | ITGB2 3304/4885ICAM1 1315/4885ITGAL 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.