Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565738 | 0.83 | KMT2A (0.48) | HTR2AHTR2CALDH1A1L3MBTL1TSHR | |
| SCHEMBL14565729 | 0.81 | PKM (0.46) | PKMKDM4EALDH1A1GAA | |
| SCHEMBL14565743 | 0.81 | MEN1 (0.55) | HTR2AHTR2CMAPTTSHR | |
| SCHEMBL5105476 | 0.80 | ATM (0.52) | ATMPKMHTR2AHTR2CKDM4E | |
| SCHEMBL4767334 | 0.78 | ATM (0.44) | ATMPKMHTR2AHTR2CKDM4E | |
| SCHEMBL14565734 | 0.76 | CTSK (0.49) | PKM | |
| SCHEMBL4767042 | 0.75 | ATM (0.42) | ATMPKMHTR2AHTR2CKDM4E | |
| SCHEMBL4898677 | 0.75 | CTSK (0.47) | ATMPKMKDM4E | |
| SCHEMBL14565744 | 0.75 | PKM (0.49) | PKMKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL1014809 | 0.75 | PKM (0.67) | ATMPKMHTR2AHTR2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196099-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-27 | — | — | US | disclosed |