Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557775 | 0.88 | MEN1 (0.36) | MEN1KMT2AHRH3DPP4NPSR1 | |
| SCHEMBL14569546 | 0.77 | HRH3 (0.48) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14569599 | 0.76 | EPHX2 (0.48) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14569506 | 0.76 | ALDH1A1 (0.50) | NPC1RAB9AHPGDALDH1A1TSHR | |
| SCHEMBL14569706 | 0.76 | EPHX2 (0.40) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14610876 | 0.76 | EPHX2 (0.48) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14569600 | 0.75 | DPP4 (0.41) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14569542 | 0.73 | RIPK1 (0.49) | EPHX2MEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL14569491 | 0.72 | EPHX2 (0.41) | EPHX2MEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL14569576 | 0.71 | DPP4 (0.46) | NPC1RAB9AHPGDALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | VCAM1, ITGB4, ICAM1 | EPHX2 3415/4885NPC1 3300/4885RAB9A 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.