Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972352 | 0.81 | RAB9A (0.53) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL10504210 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL22245544 | 0.79 | NPC1 (0.46) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL15223589 | 0.76 | KMT2A (0.44) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL17409847 | 0.76 | NPC1 (0.46) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL10506224 | 0.76 | KMT2A (0.63) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL15503715 | 0.76 | RAB9A (1.00) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL18932460 | 0.75 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL10504321 | 0.74 | SMN1; SMN2 (0.58) | NPC1RAB9AALDH1A1KMT2ATYK2 | |
| SCHEMBL14964949 | 0.73 | KEAP1 (0.48) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480539-B1 | N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-31 | — | — | EP | disclosed |
| US-8288316-B2 | N-(1,2,5-oxadiazol-3-yl)benzamides and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-10-16 | — | — | US | disclosed |
| EP-2480539-A1 | N-(1,2,5-OXADIAZOL-3-YL) BENZAMIDES AND THE USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-20110152084-A1 | N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011035874-A1 | N-(1,2,5-OXADIAZOL-3-YL) BENZAMIDES AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-03-31 | — | — | WO | disclosed |
| EP-0173657-B1 | COMPOSITIONS CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS HERBICIDES | ENICHEM SYNTHESIS S.p.A. (IT) | 1989-12-20 | — | — | EP | disclosed |
| US-4671818-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ENICHEM SINTESI S.P.A. (IT) | 1987-06-09 | — | — | US | disclosed |
| EP-0173657-A2 | Compositions containing heterocyclic compounds and their use as herbicides | ENICHEM SYNTHESIS S.p.A. (IT) | 1986-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152084-A1 | N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES | AOX1, CBR3, ZYX | NPC1 4158/4885RAB9A 3776/4885ALDH1A1 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.