Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146100 | 0.74 | MAPT (0.39) | KEAP1NFE2L2POLBKMT2AMAPT | |
| SCHEMBL9146106 | 0.74 | MAPT (0.39) | KEAP1NFE2L2POLBKMT2AMAPT | |
| SCHEMBL24574228 | 0.74 | KEAP1 (0.62) | KEAP1NFE2L2NPC1RAB9APOLB | |
| SCHEMBL1457591 | 0.73 | NPC1 (0.63) | NPC1RAB9APOLBKMT2AMAPT | |
| SCHEMBL31048876 | 0.72 | KEAP1 (0.65) | KEAP1NFE2L2NPC1RAB9APOLB | |
| SCHEMBL22245544 | 0.71 | NPC1 (0.46) | NPC1RAB9ARXFP1POLBKMT2A | |
| SCHEMBL12491903 | 0.71 | NPC1 (0.50) | NPC1RAB9ARXFP1POLBKMT2A | |
| SCHEMBL14972352 | 0.71 | RAB9A (0.53) | NPC1RAB9ARXFP1POLBKMT2A | |
| SCHEMBL20788868 | 0.69 | KEAP1 (0.61) | KEAP1NFE2L2NPC1RAB9APOLB | |
| SCHEMBL10504210 | 0.69 | ALDH1A1 (0.58) | NPC1RAB9ARXFP1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309115-A1 | Substituted 1,2,5-oxadiazole compounds and their use as herbicides III | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| US-20140309115-A1 | Substituted 1,2,5-oxadiazole compounds and their use as herbicides III | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| US-20140309115-A1 | Substituted 1,2,5-oxadiazole compounds and their use as herbicides III | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| EP-2780340-A1 | SUBSTITUTED 1,2,5-OXADIAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES III | BASF SE (DE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072450-A1 | SUBSTITUTED 1,2,5-OXADIAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES III | BASF SE (DE) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072450-A1 | SUBSTITUTED 1,2,5-OXADIAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES III | BASF SE (DE) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309115-A1 | Substituted 1,2,5-oxadiazole compounds and their use as herbicides III | CBR3, CBR1, NOX3 | KEAP1 154/4885NFE2L2 2328/4885NPC1 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.