Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582233 | 0.84 | — | — | |
| SCHEMBL14582228 | 0.74 | P2RX3 (0.47) | HRH4 | |
| SCHEMBL14612959 | 0.69 | ALDH1A1 (0.34) | HRH4 | |
| SCHEMBL8353258 | 0.67 | ALDH1A1 (0.67) | HRH4 | |
| SCHEMBL14612958 | 0.65 | USP2 (0.32) | — | |
| SCHEMBL12316235 | 0.61 | THRA (0.34) | — | |
| SCHEMBL25822427 | 0.60 | NPC1 (0.42) | — | |
| SCHEMBL1106137 | 0.59 | DGAT1 (0.33) | — | |
| SCHEMBL23966683 | 0.59 | POLB (0.33) | — | |
| SCHEMBL14582231 | 0.59 | HCRTR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032518-A1 | Compounds and methods of use | AMGEN INC. (US) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032518-A1 | Compounds and methods of use | BAX, BAD, CASP3 | CHEK1 643/4885HRH4 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.