Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL10790520 | 0.89 | CA12 (0.61) | CA2CA4CA12CA1GLA | |
| Phenol SCHEMBL8029599 | 0.89 | CA12 (0.61) | CA2CA4CA12CA1GLA | |
| Biphenyl SCHEMBL27419462 | 0.84 | PTPN5 (0.48) | CA2CA4CA14CFTRFDPS | |
| Phenol SCHEMBL28394139 | 0.84 | CA2 (0.55) | CA2CA4CA12CA1GLA | |
| Phenol SCHEMBL20264 | 0.83 | CA2 (0.69) | CA2CA4CA12CA1GLA | |
| Phenol SCHEMBL3974837 | 0.83 | CA2 (0.69) | CA2CA4CA12CA1GLA | |
| Phenol SCHEMBL131695 | 0.83 | CA2 (0.69) | CA2CA4CA12CA1GLA | |
| Phenol SCHEMBL20139217 | 0.83 | CA2 (0.69) | CA2CA4CA12CA1GLA | |
| Phenol SCHEMBL4249298 | 0.83 | CA2 (0.69) | CA2CA4CA12CA1GLA | |
| Phenol SCHEMBL18045508 | 0.83 | CA2 (0.69) | CA2CA4CA12CA1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301924-B1 | METHOD FOR PRODUCING 2,4,6-TRIS(HYDROXYPHENYL)-1,3,5-TRIAZINE COMPOUND | ADEKA CORP (JP) | 2015-09-02 | — | — | EP | disclosed |
| EP-2573076-B1 | Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound | ADEKA CORP (JP) | 2014-08-20 | — | — | EP | disclosed |
| US-8716474-B2 | Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound | ADEKA CORPORATION (JP) | 2014-05-06 | — | — | US | disclosed |
| CN-102056906-B | Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound | ADEKA CORP | 2014-02-12 | — | — | CN | disclosed |
| EP-2573076-A1 | Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound | Adeka Corporation (JP) | 2013-03-27 | — | — | EP | disclosed |
| CN-102056906-A | Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound | ADEKA CORP | 2011-05-11 | — | — | CN | disclosed |
| US-20110087023-A1 | METHOD FOR PRODUCING 2,4,6-TRIS(HYDROXYPHENYL)-1,3,5-TRIAZINE COMPOUND | ADEKA CORPORATION (JP) | 2011-04-14 | — | — | US | disclosed |
| EP-2301924-A1 | METHOD FOR PRODUCING 2,4,6-TRIS(HYDROXYPHENYL)-1,3,5-TRIAZINE COMPOUND | Adeka Corporation (JP) | 2011-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110087023-A1 | METHOD FOR PRODUCING 2,4,6-TRIS(HYDROXYPHENYL)-1,3,5-TRIAZINE COMPOUND | QSOX1, TST, TH | CA2 37/4885CA4 12/4885CA12 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.